- Product Details
Keywords
- Methyl 2-(tert-butoxycarbonylamino)-3-nitrobenzoate
- Benzoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-nitro-methyl ester
- Azilsartan & Candesartan Cilexetil intermediates
Quick Details
- ProName: BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)...
- CasNo: 57113-90-3
- Molecular Formula: C13H16N2O6
- Appearance: Solid
- Application: It can be used as a pharmaceutical syn...
- PackAge: 25kg/drum or bag
- Port: CHINA MAIN PORT
- ProductionCapacity: /
- Purity: 99%
- Storage: Sealed in dry, Room Temperature
- Transportation: by sea or by air
- LimitNum: 0
Superiority
Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.
Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.
The competitive advantages of Colorcom international as your business partner or supplier:
1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.
Details
Common name: Methyl 2-((tert-butoxycarbonyl)-amino)-3-nitrobenzoate
Category:Azilsartan & Candesartan Cilexetil intermediates
Other name: BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER
CAS No.: 57113-90-3
EINECS No.: 611-470-7
Appearance: Solid
Molecular formula: C13H16N2O6
Brand Name: Colorcom
Shelf Life: 2 Years
Place of Origin: China
Product Specification:
Molecular Weight |
296.28 |
Boiling point |
376.9±32.0 °C(Predicted) |
Melting point |
104.0 to 108.0 °C |
Density |
1.298±0.06 g/cm3(Predicted) |
Purity |
≥99.0% |
PH |
/ |
Acidity coefficient (pKa) |
11.96±0.70(Predicted) |
Soluble |
Dissolved in dichloromethane |
Water solubility |
/ |
Color |
Light yellow |
Product Description:
Methyl 2 - ((tert - butoxycarbonyl)-amino)-3 - nitrobenzoate usually presents as a white to off - white crystalline solid. Structurally, it contains a benzene ring with a methyl ester group (-COOCH?) at the 1 - position, a nitro group (-NO?) at the 3 - position, and a 2 - ((tert - butoxycarbonyl)-amino) group at the 2 - position. The nitro group is highly electron - withdrawing, which significantly affects the electron density of the benzene ring and thus its reactivity. It can participate in reduction reactions to form amino - derivatives. The 2 - ((tert - butoxycarbonyl)-amino) group, with the bulky tert - butoxycarbonyl protecting group, not only protects the amino group from unwanted reactions but also influences the molecule's solubility and physical properties. The methyl ester group can undergo hydrolysis under acidic or basic conditions to yield the corresponding carboxylic acid, and can also participate in trans - esterification reactions.
In terms of solubility, it has low solubility in water due to the relatively non - polar benzene ring and the hydrophobic tert - butoxycarbonyl group. However, it shows good solubility in polar organic solvents such as ethanol, acetone, and dichloromethane. Under normal storage conditions, it is relatively stable. But exposure to strong acids, strong bases, or heat can cause decomposition or chemical reactions. For example, in the presence of strong acids, the tert - butoxycarbonyl protecting group can be removed, liberating the free amino group.
In the field of organic synthesis, Methyl 2 - ((tert - butoxycarbonyl)-amino)-3 - nitrobenzoate is a valuable intermediate. It can be used to synthesize a wide range of nitrogen - containing aromatic compounds. By reacting its functional groups with different reagents, such as reducing agents to convert the nitro group or reagents to modify the methyl ester group, more complex molecules can be constructed. In pharmaceutical research, it may serve as a starting material for the synthesis of drugs with potential biological activities related to its aromatic and nitrogen - containing structure. To maintain its quality and reactivity, it should be stored in a cool, dry place, away from light, heat, moisture, and strong oxidizing or reducing agents.
Application:
It can be used as a pharmaceutical synthesis intermediate, such as the preparation of Candesartan intermediates.
Package: 25kg/drum or bag
Storage: Sealed in dry, Room Temperature
Executive Standards: International Standard.