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Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

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1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Common name: (5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone

Category:Empagliflozin intermediates

Other name: Methanone, [5-Bromo-2-Chloro-phenyl](4-Fluoro Phenyl)

CAS No.: 915095-85-1

EINECS No.: /

Appearance: Solid

Molecular formula: C13H7BrClFO

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

Product Specification:

Product Description:
(5 - Bromo - 2 - chlorophenyl)(4 - fluorophenyl)methanone commonly presents as a white to off - white crystalline solid. Structurally, it consists of a ketone group bridging a 5 - bromo - 2 - chlorophenyl ring and a 4 - fluorophenyl ring. The bromine, chlorine, and fluorine atoms, being electronegative halogen atoms, endow the molecule with distinct electronic properties. The bromine atom in the 5 - bromo - 2 - chlorophenyl group can participate in substitution reactions, such as nucleophilic substitution reactions with appropriate nucleophiles. The chlorine atom can also contribute to the molecule's reactivity in similar reactions. The fluorine atom in the 4 - fluorophenyl group not only affects the electron density of the phenyl ring but also can influence the intermolecular interactions due to its small size and high electronegativity. The ketone group (-C=O) is highly reactive, being prone to nucleophilic addition reactions with various nucleophiles like amines, alcohols, and Grignard reagents.

In terms of solubility, it has low solubility in water because of the relatively non - polar nature of the two phenyl rings. However, it shows good solubility in common organic solvents such as dichloromethane, chloroform, and ethyl acetate. In chemical reactions, the ketone carbonyl can be reduced to an alcohol using reducing agents like sodium borohydride. The halogen - substituted phenyl rings can undergo reactions such as metal - catalyzed cross - coupling reactions under suitable conditions.

In the fields of organic synthesis and pharmaceutical research, (5 - Bromo - 2 - chlorophenyl)(4 - fluorophenyl)methanone is of great importance. In organic synthesis, it serves as a key building block for constructing more complex aromatic compounds. By reacting its various functional groups with different reagents, a wide range of multi - functionalized molecules can be synthesized. In pharmaceutical research, it may act as a potential intermediate for the synthesis of drugs with specific biological activities. Modifying the substituents on the phenyl rings or reacting the ketone group with different compounds can potentially lead to the discovery of novel bioactive substances. To maintain its quality and reactivity, it should be stored in a cool, dry place, away from light, heat, moisture, and strong oxidizing or reducing agents.

Application: 

In organic synthesis, (5 - Bromo - 2 - chlorophenyl)(4 - fluorophenyl)methanone is a crucial building block. It can be used to construct complex aromatic compounds through reactions like metal - catalyzed cross - coupling and nucleophilic substitution. In pharmaceutical research, it serves as a potential intermediate. By modifying its functional groups, researchers can synthesize novel bioactive substances, offering possibilities for the development of new drugs with specific therapeutic effects.

Package: 25kg/drum or bag

Storage: 2-8°C

Executive Standards: International Standard.