Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.

Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

The competitive advantages of Colorcom international as your business partner or supplier:

1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Common name: Fmoc-NH-PEG3-CH2COOH

Category:PROTAC linker

Other name: Fmoc-9-amino-4,7-dioxanonanoic acid

CAS No.: 139338-72-0

EINECS No.: /

Appearance: Liquid

Molecular formula: C23H27NO7

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

Product Specification:

Product Description:
Fmoc - NH - PEG3 - CH2COOH usually exists as a white to off - white solid powder. Structurally, it is composed of a fluorenylmethyloxycarbonyl (Fmoc) group, which is a bulky and hydrophobic protecting group for the amino group. The Fmoc group can be removed under mild basic conditions, unmasking the amino group for further reactions. Attached to the Fmoc group is a polyethylene glycol (PEG) chain with three repeating ethylene oxide units (PEG3). The PEG chain imparts hydrophilicity to the molecule, enhancing its solubility in water and polar solvents. At the end of the PEG chain, there is a carboxyl - containing methylene group (CH2COOH). This carboxyl group provides the compound with acidic properties and serves as a reactive site for forming amide bonds with amines or ester bonds with alcohols under appropriate reaction conditions.

In terms of solubility, due to the presence of the PEG chain, it has good solubility in water, as well as in polar organic solvents like dimethyl sulfoxide (DMSO) and N,N - dimethylformamide (DMF). In chemical reactions, the Fmoc - protected amino group remains relatively stable under normal conditions but can be deprotected when needed. The carboxyl group can react with a variety of reagents. For example, it can be activated and then react with primary or secondary amines to form amide bonds in peptide - like synthesis.

In the fields of peptide synthesis, drug delivery research, and materials science, Fmoc - NH - PEG3 - CH2COOH is highly significant. In peptide synthesis, it is used as a building block to introduce a PEG - linked amino - acid - like moiety, which can modify the properties of peptides, such as improving their solubility and stability. In drug delivery research, the PEG chain can be used to conjugate drugs or drug - like molecules, enhancing their biocompatibility and circulation time in the body. In materials science, it can be used to prepare functional polymers with unique hydrophilic - hydrophobic properties. To maintain its quality and reactivity, it should be stored in a cool, dry place, away from light, heat, and strong oxidizing agents.

Application: 

In peptide synthesis, Fmoc - NH - PEG3 - CH2COOH serves as a building block to modify peptide properties like solubility and stability. In drug delivery research, it conjugates with drugs to enhance biocompatibility and circulation time. In materials science, it's used to prepare functional polymers with special hydrophilic - hydrophobic properties.

Package: 25kg/drum or bag

Storage: 2-8°C

Executive Standards: International Standard.