- Product Details
Keywords
- 1-[(2'-Cyano-1,1'-biphenyl-4-yl)methyl]-2-ethoxy-7-benzimidazolecarboxylicacid methyl ester
- 3-[(2'-Cyanobiphenyl-4-yl)methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acidmethyl ester
- Methyl1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylate
Quick Details
- ProName: Methyl 1-[(2'-cyanobiphenyl-4-yl)methy...
- CasNo: 139481-44-0
- Molecular Formula: C25H21N3O3
- Appearance: Solid
- Application: Angiotensin II receptor antagonist, us...
- PackAge: 25kg/drum or bag
- Port: CHINA MAIN PORT
- ProductionCapacity: /
- Purity: 99%
- Storage: 2-8°C
- Transportation: by sea or by air
- LimitNum: 0
Superiority
Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.
Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.
The competitive advantages of Colorcom international as your business partner or supplier:
1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.
Details
Common name:Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
Category:Azilsartan & Candesartan Cilexetil intermediates
Other name: 1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-, methyl ester
CAS No.: 139481-44-0
EINECS No.: 604-137-2
Appearance: Solid
Molecular formula: C25H21N3O3
Brand Name: Colorcom
Shelf Life: 2 Years
Place of Origin: China
Product Specification:
Molecular Weight |
411.45 |
Boiling point |
/ |
Melting point |
168 °C |
Density |
/ |
Purity |
≥99.0% |
PH |
/ |
Acidity coefficient (pKa) |
/ |
Soluble |
Soluble in chloroform (slight), methanol (slight, ultrasonic treatment) |
Water solubility |
/ |
Color |
Off-white to light yellow |
Product Description:
Methyl 1 - [(2'-cyanobiphenyl - 4 - yl)methyl]-2 - ethoxy - 1H - benzimidazole - 7 - carboxylate typically presents as a white to off - white crystalline solid. Structurally, it consists of a benzimidazole ring system. At the 1 - position, there is a [(2'-cyanobiphenyl - 4 - yl)methyl] group attached. The 2 - ethoxy group at the 2 - position imparts certain polarity and reactivity to the molecule. The cyanobiphenyl moiety, with its cyano group (-CN) and the biphenyl structure, not only contributes to the molecule's lipophilicity but also provides sites for potential chemical reactions. The cyano group can participate in nucleophilic addition and condensation reactions. The benzimidazole ring contains two nitrogen atoms, which can be involved in acid - base interactions and other chemical processes. At the 7 - position, a carboxylate methyl ester group (-COOCH?) is present, which can be hydrolyzed under acidic or basic conditions to yield the corresponding carboxylic acid or can be used in ester - exchange reactions.
In terms of solubility, it has low solubility in water due to the relatively non - polar nature of the biphenyl and benzimidazole rings. However, it shows good solubility in polar organic solvents such as ethanol, acetone, and dichloromethane. In chemical reactions, the ethoxy group can be cleaved under certain conditions, and the carboxylate methyl ester can be modified to introduce different functional groups.
In the fields of organic synthesis and pharmaceutical research, Methyl 1 - [(2'-cyanobiphenyl - 4 - yl)methyl]-2 - ethoxy - 1H - benzimidazole - 7 - carboxylate is of great significance. In organic synthesis, it serves as a key building block for constructing more complex molecules. By reacting its various functional groups with different reagents, a wide range of multi - functionalized compounds can be synthesized. In pharmaceutical research, it may act as a potential intermediate for the synthesis of drugs with specific biological activities. Modifying the substituents on the benzimidazole or biphenyl rings can potentially lead to the discovery of novel bioactive substances. To maintain its quality and reactivity, it should be stored in a cool, dry place, away from light, heat, moisture, and strong oxidizing or reducing agents.
Application:
Angiotensin II receptor antagonist, used to treat hypertension.
Package: 25kg/drum or bag
Storage: 2-8°C
Executive Standards: International Standard.