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1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Common name: 4-Hydroxythiobenzamide

Category:Febuxostat intermediates

Other name: p-HydroxyThioBenzamide

CAS No.: 25984-63-8

EINECS No.: 674-712-0

Appearance: Solid

Molecular formula: C7H7NOS

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

Product Specification:

Product Description:
4 - Hydroxythiobenzamide typically appears as a white to light - yellow crystalline solid. Structurally, it consists of a benzene ring with a hydroxyl group at the para - position and a thiobenzamide moiety. The hydroxyl group imparts certain polarity and reactivity to the molecule, enabling it to participate in hydrogen - bonding interactions and various substitution reactions. The thiobenzamide group, with its sulfur - containing carbonyl - like structure, also contributes to the compound's unique chemical properties. The sulfur atom in the thiobenzamide can act as a nucleophile in some reactions, and the carbonyl - like group can participate in reactions typical of amides, such as hydrolysis under acidic or basic conditions.

In terms of solubility, it has limited solubility in water due to the relatively non - polar benzene ring, but it shows better solubility in polar organic solvents like ethanol, methanol, and N,N - dimethylformamide (DMF). In chemical reactions, the hydroxyl group can be acetylated or alkylated under appropriate conditions. The thiobenzamide group can be involved in reactions with electrophiles, and the amide bond can be cleaved to form the corresponding carboxylic acid or amine derivatives.

In the fields of organic synthesis and pharmaceutical research, 4 - Hydroxythiobenzamide is of significance. In organic synthesis, it serves as a useful building block for constructing more complex molecules. For example, by reacting the hydroxyl and thiobenzamide groups with different reagents, a variety of functionalized compounds can be obtained. In pharmaceutical research, it may be a potential intermediate for the synthesis of drugs with specific biological activities. Modifying the substituents on the benzene ring or the functional groups attached to it can potentially lead to the discovery of novel bioactive substances. To maintain its quality and reactivity, it should be stored in a cool, dry environment, away from moisture, heat, and strong oxidizing agents.

Application: 

4-hydroxythiobenzamide is an intermediate in organic synthesis and pharmaceutical research and development. In the process of organic synthesis and pharmaceutical research and development, it can mainly be used to synthesize febuxotam as a raw material.

Package: 25kg/drum or bag

Storage: Keep in dark place, Inert atmosphere, Room temperature

Executive Standards: International Standard.