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Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

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1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
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11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Common name: 6-Chloro-3-methyluracil

Category:Trelagliptin & Alogliptin intermediates

Other name: 6-chloro-3-methyl-2,4(1H,3H)-pyrimidinedione

CAS No.: 4318-56-3

EINECS No.: 610-113-2

Appearance: Powder

Molecular formula: C5H5ClN2O2

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

Product Specification:

Product Description:
6 - Chloro - 3 - methyluracil commonly appears as a white to off - white crystalline powder. Structurally, it belongs to the pyrimidine derivative family, with a uracil core structure. The uracil ring consists of a six - membered heterocyclic ring containing two nitrogen atoms and two carbonyl groups. At the 3 - position, a methyl group is attached, and at the 6 - position, a chlorine atom is present. The methyl group at the 3 - position can influence the molecule's physical properties and reactivity by changing the electron density of the ring. The chlorine atom at the 6 - position, being electronegative, makes this carbon atom more electrophilic, which is crucial for its participation in various chemical reactions, especially substitution reactions.

In terms of solubility, it has low solubility in water due to the relatively non - polar nature of the pyrimidine ring and the hydrophobic methyl group. However, it shows better solubility in polar organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and N,N - dimethylformamide (DMF). Under normal storage conditions, it is relatively stable. But exposure to strong acids, strong bases, or high temperatures can cause decomposition or chemical reactions. For example, in the presence of strong bases, the chlorine atom can be substituted by a nucleophile, leading to the formation of new derivatives.

In the field of organic synthesis, 6 - Chloro - 3 - methyluracil is a significant intermediate. It can be used to synthesize a wide range of pyrimidine - based compounds with diverse applications. In the pharmaceutical industry, it is of great interest as many pyrimidine - containing compounds exhibit important biological activities. It may serve as a starting material for the synthesis of drugs that target specific biological pathways related to nucleic acid metabolism, cell growth, and replication. In the agricultural field, derivatives synthesized from it might be used in the development of herbicides or pesticides. To maintain its quality and reactivity, it should be stored in a cool, dry place, away from light, heat, moisture, and reactive chemicals.

Application: 

6-chloro-3-methyluracil has been used in the synthesis of antimicrobial agents as an inhibitor of Helicobacter pylori glutamate racemase.

Package: 25kg/drum or bag

Storage: Inert atmosphere, Room Temperature

Executive Standards: International Standard.