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Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

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1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Common name: (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone

Category:Empagliflozin intermediates

Other name: 2-Chloro-4'-fluoro-5-iodobenzophenone

CAS No.: 915095-86-2

EINECS No.: 619-596-4

Appearance: Solid

Molecular formula: C13H7ClFIO

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

Product Specification:

Product Description:
(2 - Chloro - 5 - iodophenyl)(4 - fluorophenyl)methanone usually appears as a pale - yellow to light - brown crystalline solid. Structurally, it features a ketone group connecting a 2 - chloro - 5 - iodophenyl ring and a 4 - fluorophenyl ring. The chlorine, iodine, and fluorine atoms, all being electronegative halogens, confer unique electronic characteristics to the molecule. The chlorine atom in the 2 - chloro - 5 - iodophenyl group can take part in substitution reactions, for instance, nucleophilic substitution reactions when reacting with proper nucleophiles. The iodine atom, with its large size and relatively polarizable electron cloud, also contributes to the molecule's reactivity. It can be involved in reactions such as metal - catalyzed coupling reactions. The fluorine atom in the 4 - fluorophenyl group affects the electron density of the phenyl ring and can influence intermolecular forces due to its high electronegativity and small size. The ketone group (-C=O) is highly reactive and is likely to undergo nucleophilic addition reactions with various nucleophiles, including amines, alcohols, and organometallic reagents like Grignard reagents.

In terms of solubility, due to the non - polar nature of the two phenyl rings, it has poor solubility in water. However, it shows good solubility in common organic solvents like dichloromethane, chloroform, and ethyl acetate. In chemical reactions, the ketone carbonyl can be reduced to an alcohol using reducing agents such as sodium borohydride. The halogen - substituted phenyl rings can participate in reactions like cross - coupling reactions under appropriate conditions.

In the areas of organic synthesis and pharmaceutical research, (2 - Chloro - 5 - iodophenyl)(4 - fluorophenyl)methanone is of great significance. In organic synthesis, it acts as a valuable building block for creating more complex aromatic compounds. By reacting its different functional groups with diverse reagents, a wide variety of multi - functional molecules can be synthesized. In pharmaceutical research, it may serve as a potential intermediate for the synthesis of drugs with specific biological activities. Modifying the substituents on the phenyl rings or reacting the ketone group with different substances can potentially lead to the discovery of novel bioactive substances. To maintain its quality and reactivity, it should be stored in a cool, dry environment, away from light, heat, moisture, and strong oxidizing or reducing agents.

Application: 

It is an intermediate in the synthesis of epalegine

Package: 25kg/drum or bag

Storage: Under inert gas (nitrogen or Argon) at 2–8 °C

Executive Standards: International Standard.